Heart Muscle
Carries androgen receptors like skeletal muscle does, and thickens under the same signal. Unlike a bicep, a thicker left ventricle fills less well.
Relationships
5 connectionsHeart Muscle expressed in
Androgen Receptor
The receptor every anabolic-androgenic steroid is designed to hit. Binding moves it into the nucleus where it switches on genes for muscle protein synthesis, and in other tissues for hair loss, prostate growth and oil production.
GLP-1 Receptor
The incretin receptor behind semaglutide and every drug in that class. Three separate effects run through it: appetite suppression in the brain, slower stomach emptying, and glucose-dependent insulin release from the pancreas.
IGF-1 Receptor
The receptor that carries almost all of growth hormone's anabolic effect, one step downstream of it. It is also the reason the IGF-1 analogs are the peptides with the most serious theoretical cancer question: the same signal that grows muscle grows anything already growing.
Oxytocin Receptor
Oxytocin's receptor, and it is not only in the brain. The uterus, heart, gut and T-cells all carry it, which is why an intranasal dose taken for mood also has cardiovascular and gut effects.