Growth Hormone Receptor
GHRWhere growth hormone itself acts. Binding pairs the receptor and fires JAK2/STAT5, which in the liver means IGF-1 output and in fat means lipolysis. Injected GH works here; secretagogues work one step upstream.
Relationships
4 connectionsGrowth Hormone Receptor expressed in
Adipose Tissue
Stores fat and houses most of the body's aromatase, so more fat mass means more conversion of androgen to estrogen.
Bone Marrow
Where red cells are built. Androgens push it harder, which is why they were once a treatment for anaemia and why haematocrit climbs on cycle.
Liver
Processes every oral steroid on first pass. The 17-alpha-alkyl group that lets an oral survive that trip is also what makes it hard on this organ.
Skeletal Muscle
The intended target. Dense in androgen receptors, and the tissue where the whole risk trade is being made.
Beyond this page
Growth Hormone Receptor also connects to 1 entry in the applied modules, covering supplements, compounds, hormones and food sources. Those carry the mechanism and the evidence tier behind each link, and they are part of client coaching.
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