Skip to main content

Anterior Cingulate Cortex

dACC
Tissue Cns

Where conflict is detected and effort is allocated. In long-term users this region shows a chemical signature of altered glutamate handling, which is the closest thing in the human literature to direct evidence of a neurotoxic process.

Relationships

2 connections

Anterior Cingulate Cortex elevates

Glutamate Signalling

The brain's main excitatory signal. Everything fast the brain does runs on it, and too much of it is how neurons die. Long-term users show a chemical signature consistent with raised turnover, which is the nearest thing to direct human evidence of a neurotoxic process in this literature.

Anterior Cingulate Cortex stimulates

Executive Function

Planning, switching between tasks, and holding back a response you are about to make. The last of those is the one that matters here: reported aggression on these compounds is often better described as a failure of the brake than as an increase in anger.

Beyond this page

Anterior Cingulate Cortex also connects to 1 entry in the applied modules, covering supplements, compounds, hormones and food sources. Those carry the mechanism and the evidence tier behind each link, and they are part of client coaching.

Get your free assessment