Sebaceous Gland
Tissue
Dermatologic
Oil glands in the skin. Androgen signalling raises output, and heavier oil plus keratin plugging is how steroid acne starts.
Relationships
3 connectionsSebaceous Gland expressed in
Androgen Receptor
The receptor every anabolic-androgenic steroid is designed to hit. Binding moves it into the nucleus where it switches on genes for muscle protein synthesis, and in other tissues for hair loss, prostate growth and oil production.
Melanocortin 5 Receptor
The melanocortin receptor on sebaceous and other exocrine glands. Pan-melanocortin agonists hit it, which is part of why they can trigger oil production and acne alongside the tan.