Gynecomastia
Glandular breast tissue growth in men. Two separate routes reach it, estrogen and prolactin, and treating the wrong one does nothing.
Relationships
3 connectionsGynecomastia increases risk of
Breast Duct Growth
Growth of the duct tissue behind the nipple, driven by oestrogen and progesterone signalling. Once it has laid down glandular tissue it does not reliably regress.
Estrogen Receptor alpha
The estrogen receptor that dominates breast tissue, liver and the pituitary feedback loop. Gynecomastia and much of the negative feedback on LH run through it.
Progesterone Receptor
The progesterone receptor. 19-nor steroids are structurally close enough to progesterone to activate it, which is why nandrolone and trenbolone produce progestogenic side effects that an aromatase inhibitor cannot touch.
Beyond this page
Gynecomastia also connects to 16 entries in the applied modules, covering supplements, compounds, hormones and food sources. Those carry the mechanism and the evidence tier behind each link, and they are part of client coaching.
Get your free assessment