Ghrelin Receptor
GHSR-1aWhat ghrelin binds to make the pituitary release growth hormone, and what every GHRP and MK-677 is built to hit. It also carries the hunger signal, which is why some GH secretagogues make you ravenous and others do not.
Relationships
3 connectionsGhrelin Receptor expressed in
Anterior Pituitary
The gland that actually releases growth hormone, LH and FSH. Every GH secretagogue and every GnRH drug is aimed here, not at the tissue where the effect is finally felt.
Hypothalamus
The control room above the pituitary. Appetite, body temperature, the reproductive axis and the GH rhythm are all set here, which is why so many peptides that produce whole-body effects act on one small area.
Stomach
Where ghrelin is produced and where GLP-1 agonists slow emptying. That slowing is both the satiety mechanism and the source of the nausea.
Beyond this page
Ghrelin Receptor also connects to 4 entries in the applied modules, covering supplements, compounds, hormones and food sources. Those carry the mechanism and the evidence tier behind each link, and they are part of client coaching.
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