Estrogen Receptor beta

ER-beta

Receptor Endocrine

The second estrogen receptor, common in brain, bone and vascular tissue. Part of why estradiol is needed for mood, libido and bone density rather than being purely a side effect to crush.

Relationships

4 connections

Estrogen Receptor beta expressed in

Limbic System

The emotional core of the brain, and androgen-receptor rich. This is where mood, threat response and aggression are set, and where steroid mental effects are thought to land.

Vascular Endothelium

The single-cell lining of every blood vessel. It sets vessel tone and is where plaque begins when lipids and pressure both move the wrong way.

Estrogen Receptor beta reduces risk of

Depressed Mood

Low mood, flat drive and anhedonia. Concentrated in the withdrawal window after a cycle, when natural testosterone has not yet restarted.

Estrogen Receptor beta stimulates

Mood and Wellbeing

Day-to-day mood and sense of wellbeing, as distinct from a diagnosable mood disorder. It moves in both directions on these compounds, and the direction is not predictable from how strong the compound is.

Beyond this page

Estrogen Receptor beta also connects to 1 entry in the applied modules, covering supplements, compounds, hormones and food sources. Those carry the mechanism and the evidence tier behind each link, and they are part of client coaching.

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