Breast Tissue
Responds to both estrogen and prolactin. Once glandular tissue forms it does not go away on its own, which is why this one is worth preventing rather than treating.
Relationships
4 connectionsBreast Tissue expressed in
Estrogen Receptor alpha
The estrogen receptor that dominates breast tissue, liver and the pituitary feedback loop. Gynecomastia and much of the negative feedback on LH run through it.
Progesterone Receptor
The progesterone receptor. 19-nor steroids are structurally close enough to progesterone to activate it, which is why nandrolone and trenbolone produce progestogenic side effects that an aromatase inhibitor cannot touch.
Prolactin Receptor
What prolactin acts through, including in breast tissue. It is the reason a progestogenic compound can produce gyno with a perfectly normal estradiol reading.